Neutron capture therapy
Key question for further development of NCT:
- Development of targeted drug agents, containing B-10 or Gd-157 (delivery of high levels of B-10 or Gd-157 tumor cells)
- Compact sources of thermal neutrons
- Treatment planning systems for NCT
NCT has the following Indication for treatment of locally invasive malignant tumors:
- primary brain tumors
- recurrent cancers of the head and neck region
- cutaneous and extracutaneous melanomas
NCT is the the form of radiotherapy based on nuclear reaction inside tumor cells by mean of thermal neutron capture. To perform NCT either Boron-10, or Gadolinium-157 based drug should be administrated prior to the neutron irradiation.